iPTMnet Report for P78345 (RPP38)
Protein Information
UniProt AC / UniProt ID | P78345 / RPP38_HUMAN |
Protein Name | Ribonuclease P protein subunit p38 |
Gene Name | Name: RPP38 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P78345 |
PRO Name | ribonuclease P protein subunit p38 (human) |
Definition | A ribonuclease P protein subunit p38 that is encoded in the genome of human. |
Short Label | hRPP38 |
Category | organism-gene |
P78345 (RPP38) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
R10 | Methylation | score1 | PhosphoSitePlus | |||
S12 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 20068231 | ||
R14 | Methylation | score1 | PhosphoSitePlus | |||
T23 | Phosphorylation | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
C159 | Methylation | score1 | IEDB | 31844290 | ||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
T221 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
S226 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 21406692, 18669648 | ||
T234 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 20068231, 18452278 | ||
S235 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 23186163, 19664994, 19651622, ... | ||
S240 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
K241 | Acetylation | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
T255 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | T2 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R10 | Q10 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] | |
R10 | W10 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
R14 | C14 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] | |
R14 | H14 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T23 | M23 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
K111 | T111 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S226 | R226 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T234 | I234 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |