iPTMnet Report for P78337 (PITX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78337 / PITX1_HUMAN
Protein Name Pituitary homeobox 1
Gene Name Name: PITX1
Synonyms:BFT,PTX1;
Organism Homo sapiens (Human)

PRO ID PR:P78337
DAG View
PRO Name pituitary homeobox 1 (human)
Definition A pituitary homeobox 1 that is encoded in the genome of human.
Short Label hPITX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78337 (PITX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S46 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 17081983
S48 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 17081983, ...20068231
S50 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983
S51 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983, ...18452278
T53 Phosphorylation HPRD   PhosphoSitePlus 17081983
S70 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
S188 O-Glycosylation GlyGen 34846842, 33214551, 30059200, ...30620550, 31492838, 35289036, 35254053, 29237092
T196 O-Glycosylation GlyGen 34846842, 33214551, 30059200, ...35254053, 31492838, 35289036, 29237092
S284 Phosphorylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
S314 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S51 A51 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S70 N70 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]