iPTMnet Report for P78332 (RBM6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P78332 / RBM6_HUMAN
Protein Name RNA-binding protein 6
Gene Name Name: RBM6
Synonyms:DEF3;
Organism Homo sapiens (Human)

PRO ID PR:P78332
DAG View
PRO Name RNA-binding protein 6 (human)
Definition An RNA-binding protein 6 that is encoded in the genome of human.
Short Label hRBM6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P78332 (RBM6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R15 Methylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus   UniProt 23186163
K36 Methylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
R96 Methylation PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
R166 Methylation PhosphoSitePlus
R176 Methylation PhosphoSitePlus
R178 Methylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
R238 Methylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus   UniProt 23186163
T252 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
R258 Methylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
K331 Sumoylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus   UniProt 23186163
S353 Phosphorylation PhosphoSitePlus
S360 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18669648, ...24275569, 19690332
S362 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18669648, ...24275569, 19690332
S370 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
K386 Sumoylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
T447 O-Glycosylation GlyGen 30379171, 34019948, 35254053
S450 O-Glycosylation GlyGen 30379171, 34019948, 35254053
K453 Sumoylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
T468 Phosphorylation PhosphoSitePlus
K469 Sumoylation PhosphoSitePlus
K469 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
S557 Phosphorylation PhosphoSitePlus
K569 Sumoylation PhosphoSitePlus
Y701 Phosphorylation PhosphoSitePlus
K741 Sumoylation PhosphoSitePlus
K741 Ubiquitination PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
T836 Phosphorylation PhosphoSitePlus
S837 Phosphorylation PhosphoSitePlus
K840 Acetylation PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
S843 O-Glycosylation GlyGen 30379171, 34019948, 35254053
K844 Acetylation PhosphoSitePlus
K849 Acetylation PhosphoSitePlus
K871 Sumoylation PhosphoSitePlus
K887 Sumoylation PhosphoSitePlus
S891 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 17081983, 24275569
Y908 Phosphorylation PhosphoSitePlus
S912 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y914 Phosphorylation PhosphoSitePlus
T923 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
K948 Sumoylation PhosphoSitePlus
K972 Acetylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
K981 Acetylation PhosphoSitePlus
K991 Sumoylation PhosphoSitePlus
K1019 Ubiquitination PhosphoSitePlus
S1022 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1025 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...18669648, 24275569, 20068231, 17081983
S1039 Phosphorylation PhosphoSitePlus
K1046 Sumoylation PhosphoSitePlus
T1051 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus
T1062 Phosphorylation PhosphoSitePlus
K1066 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S360 Phosphorylation HPRD 17525332, 18669648, 20068231, ...18452278
S362 Phosphorylation HPRD 18691976, 17525332, 18669648, ...20068231, 18452278
S891 Phosphorylation HPRD 19651622, 18691976, 17081983, ...20068231, 18452278
S912 Phosphorylation HPRD 18669648, 20068231
T923 Phosphorylation HPRD 15302935
S1022 Phosphorylation HPRD 18691976
S1025 Phosphorylation HPRD 18691976, 16964243, 19664994, ...19664995, 18669648, 20068231, 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R15 C15 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R15 H15 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K36 M36 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R96 S96 Biomuta DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S111 A111 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S122 P122 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R176 G176 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R238 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R238 Q238 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S240 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T252 M252 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S263 T263 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S370 P370 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S373 F373 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T399 I399 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S403 I403 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T447 I447 Biomuta DOID:4159 / skin cancer [ cosmic ]
T468 R468 Biomuta DOID:1319 / brain cancer [ cosmic ]
S750 C750 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S891 I891 Biomuta DOID:3571 / liver cancer [ cosmic ]
T923 A923 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K972 E972 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K972 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K981 N981 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1062 S1062 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]