iPTMnet Report for P68431 (H3C12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P68431 / H31_HUMAN
Protein Name Histone H3.1
Gene Name Name: H3C12
Synonyms:H3FA,HIST1H3A;Synonyms:H3FL,HIST1H3B;Synonyms:H3FC HIST1H3C;Synonyms:H3FB,HIST1H3D;Synonyms:H3FD,HIST1H3E;Synonyms:H3FI,HIST1H3F;Synonyms:H3FH,HIST1H3G;Synonyms:H3FK,HIST1H3H;Synonyms:H3FF,HIST1H3I;Synonyms:H3FJ,HIST1H3J;
Organism Homo sapiens (Human)

PRO ID PR:P68431
DAG View
PRO Name histone H3.1 (human)
Definition A histone H3 that is a translation product of any of the following genes in human: HIST1H3A/HIST1H3B/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J.
Short Label hH3.1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P68431 (H3C12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
R3 Methylation UniProt 17898714, 18077460, 18079182
T4 Phosphorylation Q99986 (VRK1) phospho.ELM   PRO   UniProt 20705812, 20929775, 19622635, ...16185088, 20953165, 15681610, 17938195
K5 Acetylation PRO   UniProt 18552846, 17194708
K5 Methylation UniProt 16267050, 16457588, 17194708
T7 Phosphorylation PRO   UniProt 20228790
K10 Acetylation PRO   UniProt 20816089, 20972224, 19135889, ...16627869, 16185088, 16267050, 16457588, 17478518, 16497732, 17906200, 18337721, 17194708, 12419248, 16544193, 17403718, 21453398
K10 Methylation UniProt 16185088, 16267050, 16457588, ...17194708, 11242053
S11 O-Glycosylation GlyGen 21896475, 22371497, 28298630, ...32522876, 36357422
S11 Phosphorylation P31751 (AKT2) , P11309 (PIM1) , Q99986 (VRK1) , Q96KB5 (PBK) , Q13153 (PAK1) , Q96GD4 (AURKB) , Q16539 (MAPK14) , O14965 (AURKA) , P51812 (RPS6KA3) , P21980 (TGM2) , Q9UQB9 (AURKC) , O75582 (RPS6KA5) neXtProt   phospho.ELM   PRO   Signor   UniProt 15249581, 10436156, 12588998, ...10464286, 12082625, 12560483, 15994958, 16457588, 16651411, 12151336, 16185088, 22158034, 15681610, 11856369, 15108802, 12677454, 16982762, 20626350, 16407273, 18256527, 14583461, 14625384, 17643117, 17938195
T12 Phosphorylation O14757 (CHEK1) , O43293 (DAPK3) neXtProt   phospho.ELM   PRO   UniProt 18243098, 12560483, 18066052, ...22901803
K15 Acetylation PRO   UniProt 16627869, 16267050, 16457588, ...16497732, 16678094, 17194708, 12419248, 16185088
R18 Methylation UniProt 15345777, 15471871, 16497732
K19 Acetylation PRO   UniProt 20978174, 16627869, 18552846, ...16267050, 35939806, 15988529, 17194708, 20841388, 19349354, 18953329
K19 Methylation UniProt 16267050, 17194708
K24 Acetylation PRO   UniProt 21164480, 16267050, 16457588, ...17194708, 16627869
K24 Methylation UniProt 17194708
K28 Acetylation PRO   UniProt 18552846, 16627869, 20385584, ...17194708
K28 Methylation UniProt 16185088, 16267050, 17194708, ...16627869
S29 O-Glycosylation GlyGen 21896475, 22371497, 28298630, ...32522876, 36357422
S29 Phosphorylation P31751 (AKT2) , Q96GD4 (AURKB) , P28482 (MAPK1) , P45984 (MAPK9) , O75582 (RPS6KA5) , P27361 (MAPK3) , Q16539 (MAPK14) , P45983 (MAPK8) HPRD   neXtProt   phospho.ELM   PRO   Signor   UniProt 11856369, 22158034, 10464286, ...12082625, 16457588, 19007248, 11278789, 16185088, 21282660, 17924679, 20129940, 15681610, 15684425
T33 O-Glycosylation GlyGen 21896475, 22371497, 28298630, ...32522876, 36357422
K37 Acetylation PRO   PhosphoSitePlus   UniProt 17189264, 17194708, 18552846
K37 Methylation PhosphoSitePlus   UniProt 16627869, 16267050, 15983376, ...17194708, 16185088
K37 Ubiquitination PhosphoSitePlus
K38 Methylation UniProt 15983376
Y42 Phosphorylation PRO   UniProt 19783980
T46 O-Glycosylation GlyGen 21896475, 22371497, 28298630, ...32522876, 36357422
T46 Phosphorylation Q05655 (PRKCD) , P31751 (AKT2) neXtProt   PRO   Signor 19363025, 22158034
K57 Acetylation PRO   UniProt 19625767, 20587414, 19270680, ...17194708
K57 Methylation UniProt 22387026, 17194708
S58 Phosphorylation UniProt 20850016
K65 Methylation UniProt 16267050, 17194708
K80 Acetylation UniProt 17194708
K80 Methylation UniProt 15525939, 16267050, 17194708, ...16627869
T81 Phosphorylation UniProt 20850016
S87 Phosphorylation PhosphoSitePlus
C97 Methylation IEDB 31844290
C97 S-Nitrosylation dbSNO 25040305
C111 Methylation IEDB 31844290
K116 Acetylation UniProt 19520870
K123 Acetylation UniProt 19520870, 23415232
K123 Methylation UniProt 16267050, 17194708