iPTMnet Report for P68402 (PAFAH1B2)
Protein Information
UniProt AC / UniProt ID | P68402 / PA1B2_HUMAN |
Protein Name | Platelet-activating factor acetylhydrolase IB subunit alpha2 |
Gene Name | Name: PAFAH1B2 Synonyms:PAFAHB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P68402 |
PRO Name | platelet-activating factor acetylhydrolase IB subunit alpha2 (human) |
Definition | A platelet-activating factor acetylhydrolase IB subunit alpha2 that is encoded in the genome of human. |
Short Label | hPAFAH1B2 |
Category | organism-gene |
P68402 (PAFAH1B2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330, 21406692, 20068231 | ||
S2 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 20068231 | ||
S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
K224 | Sumoylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 20058876, ... | ||
S6 | Phosphorylation | score0 | HPRD | 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y145 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S64 | P64 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S64 | F64 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K133 | R133 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |