iPTMnet Report for P63267 (ACTG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P63267 / ACTH_HUMAN
Protein Name Actin, gamma-enteric smooth muscle precursor
Gene Name Name: ACTG2
Synonyms:ACTA3,ACTL3,ACTSG;
Organism Homo sapiens (Human)

PRO ID PR:P63267
DAG View
PRO Name actin, gamma-enteric smooth muscle (human)
Definition An actin, gamma-enteric smooth muscle that is encoded in the genome of human.
Short Label hACTG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P63267 (ACTG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
E3 Acetylation UniProt 22223895
R29 Methylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K51 Methylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
K62 Acetylation PhosphoSitePlus
K62 Sumoylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
K69 Acetylation PhosphoSitePlus
K69 Methylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
K85 Acetylation PhosphoSitePlus
K85 Methylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
R96 Methylation PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
T127 Phosphorylation PhosphoSitePlus
Y144 Phosphorylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
Y189 Phosphorylation PhosphoSitePlus
K192 Acetylation PhosphoSitePlus
K192 Methylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
T195 Phosphorylation PhosphoSitePlus
R197 Methylation PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
K214 Acetylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K216 Acetylation PhosphoSitePlus
K216 Methylation PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
K239 Methylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
T261 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
T305 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation PhosphoSitePlus
K316 Acetylation PhosphoSitePlus
K316 Sumoylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
K327 Acetylation PhosphoSitePlus
K327 Methylation PhosphoSitePlus
K327 Sumoylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K329 Acetylation PhosphoSitePlus
K329 Sumoylation PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K337 Sumoylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
Y363 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y363 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R29 L29 Biomuta DOID:1324 / lung cancer [ cosmic ]
R29 W29 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R29 P29 Biomuta DOID:4159 / skin cancer [ cosmic ]
R29 Q29 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y54 C54 Biomuta DOID:4159 / skin cancer [ cosmic ]
S61 R61 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S61 I61 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T78 I78 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S90 F90 Biomuta DOID:4159 / skin cancer [ cosmic ]
R96 H96 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y144 C144 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T150 I150 Biomuta [ cosmic ]
S156 L156 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y189 F189 Biomuta DOID:3571 / liver cancer [ cosmic ]
K192 N192 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S200 F200 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K214 R214 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S234 Y234 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S235 F235 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S240 C240 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S266 F266 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y295 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T304 I304 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K316 T316 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S324 I324 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S324 N324 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y363 N363 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]