iPTMnet Report for P62979 (RPS27A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62979 / RS27A_HUMAN
Protein Name Ubiquitin-ribosomal protein eS31 fusion protein precursor
Gene Name Name: RPS27A
Synonyms:UBA80,UBCEP1;
Organism Homo sapiens (Human)

PRO ID PR:P62979
DAG View
PRO Name ubiquitin-40S ribosomal protein S27a (human)
Definition A ubiquitin-40S ribosomal protein S27a that is encoded in the genome of human.
Short Label hRPS27A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62979 (RPS27A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Acetylation IEDB   PhosphoSitePlus 34357683
K6 Methylation PhosphoSitePlus
K6 Sumoylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus   UniProt 16443603
T7 Phosphorylation PhosphoSitePlus
K11 Acetylation PhosphoSitePlus
K11 Sumoylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus   UniProt 16443603, 16543144
T12 Phosphorylation HPRD   PhosphoSitePlus 20068231
T14 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
K27 Sumoylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus   UniProt 15466860
K29 Sumoylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus   UniProt 25752577, 16543144, 25752573, ...34239127
K33 Sumoylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus   UniProt 25752577
K48 Acetylation PhosphoSitePlus
K48 Sumoylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus   UniProt 16443603, 16543144
S57 Phosphorylation HPRD   PhosphoSitePlus 19691289
Y59 Phosphorylation PhosphoSitePlus
K63 Methylation PhosphoSitePlus
K63 Sumoylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus   UniProt 16543144, 18719106
S65 Phosphorylation HPRD   PhosphoSitePlus   UniProt 24660806, 17081983, 24784582, ...24751536, 25527291
T66 Phosphorylation PhosphoSitePlus
R72 Methylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K99 Acetylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K104 Acetylation PhosphoSitePlus   UniProt 19608861
K104 Ubiquitination PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus   UniProt 36638793
K113 Acetylation PhosphoSitePlus   UniProt 19608861
K113 Ubiquitination PhosphoSitePlus   UniProt 36638793, 32129764
S115 Phosphorylation PhosphoSitePlus
R119 Methylation PhosphoSitePlus
S123 O-Glycosylation GlyGen 23301498, 35008409, 30444036, ...35138101, 30397120, 33214551, 29351928, 34019948, 35083852, 36580660
S123 Phosphorylation PhosphoSitePlus
R138 Methylation PhosphoSitePlus
Y140 Phosphorylation PhosphoSitePlus
K143 Acetylation PhosphoSitePlus
K143 Ubiquitination PhosphoSitePlus
C144 S-Nitrosylation dbSNO 22178444
C145 S-Nitrosylation dbSNO 22178444
T147 Phosphorylation PhosphoSitePlus
Y148 Phosphorylation PhosphoSitePlus
C149 S-Nitrosylation dbSNO 22178444
K152 Acetylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 W20 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S57 C57 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y59 C59 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S84 C84 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y106 C106 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R138 I138 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T147 I147 Biomuta DOID:10283 / prostate cancer [ cosmic ]