iPTMnet Report for P62879 (GNB2)
Protein Information
UniProt AC / UniProt ID | P62879 / GBB2_HUMAN |
Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 |
Gene Name | Name: GNB2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P62879 |
PRO Name | guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (human) |
Definition | A guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 that is encoded in the genome of human. |
Short Label | hGNB2 |
Category | organism-gene |
P62879 (GNB2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330 | ||
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
R15 | Methylation | score1 | PhosphoSitePlus | |||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
C25 | S-Nitrosylation | score0 | dbSNO | 21278135 | ||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
K57 | Acetylation | score1 | PhosphoSitePlus | |||
K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
K78 | Acetylation | score1 | PhosphoSitePlus | |||
Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
C204 | S-Nitrosylation | score0 | dbSNO | 26338901, 22126794, 21278135 | ||
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
C218 | Methylation | score1 | IEDB | 31844290 | ||
Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
C317 | S-Nitrosylation | score0 | dbSNO | 21278135 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S2 | N2 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K23 | Q23 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
C25 | R25 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K57 | N57 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K89 | T89 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K89 | E89 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K209 | N209 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |