iPTMnet Report for P62714 (PPP2CB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62714 / PP2AB_HUMAN
Protein Name Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Gene Name Name: PPP2CB
Organism Homo sapiens (Human)

PRO ID PR:P62714
DAG View
PRO Name serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (human)
Definition A serine/threonine-protein phosphatase 2A catalytic subunit beta isoform that is encoded in the genome of human.
Short Label hPPP2CB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62714 (PPP2CB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
C50 Methylation IEDB 31844290
K74 Ubiquitination PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
K136 Acetylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
C165 Methylation IEDB 31844290
S212 Phosphorylation PhosphoSitePlus
Y248 Phosphorylation PhosphoSitePlus
C251 Methylation IEDB 31844290
Y265 Phosphorylation PhosphoSitePlus
C266 Methylation IEDB 31844290
K283 Ubiquitination PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
R295 Methylation PhosphoSitePlus
T304 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation PRO


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048885 (hPPP2CB/Phos:1) pY307 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T78 A78 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S212 * Biomuta DOID:263 / kidney cancer [ cosmic ]
Y265 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K283 N283 Biomuta DOID:9256 / colorectal cancer [ cosmic ]