iPTMnet Report for P62249 (RPS16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62249 / RS16_HUMAN
Protein Name Small ribosomal subunit protein uS9
Gene Name Name: RPS16
Organism Homo sapiens (Human)

PRO ID PR:P62249
DAG View
PRO Name 40S ribosomal protein S16 (human)
Definition A 40S ribosomal protein S16 that is encoded in the genome of human.
Short Label hRPS16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62249 (RPS16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus   UniProt 23186163
K4 Methylation PhosphoSitePlus
K4 Sumoylation PhosphoSitePlus
K4 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
R15 Methylation PhosphoSitePlus
C25 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
K26 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
R45 Methylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K50 Sumoylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K60 Acetylation PhosphoSitePlus   UniProt 19608861
K60 Ubiquitination PhosphoSitePlus
R62 Methylation PhosphoSitePlus
R69 Methylation PhosphoSitePlus
K73 Sumoylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
S104 O-Glycosylation GlyGen 33214551, 35138101, 34725712, ...29351928, 34019948, 35083852, 20305658, 22121020
K105 Acetylation PhosphoSitePlus
K105 Sumoylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K109 Sumoylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
R117 Methylation PhosphoSitePlus
R125 Methylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K131 Acetylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K143 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R62 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R69 S69 Biomuta DOID:363 / uterine cancer [ cosmic ]
R69 C69 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y115 * Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y115 F115 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R125 H125 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S129 P129 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K131 N131 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]