iPTMnet Report for P62241 (RPS8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P62241 / RS8_HUMAN
Protein Name Small ribosomal subunit protein eS8
Gene Name Name: RPS8
ORFNames:OK/SW-cl.83;
Organism Homo sapiens (Human)

PRO ID PR:P62241
DAG View
PRO Name 40S ribosomal protein S8 (human)
Definition A 40S ribosomal protein S8 that is encoded in the genome of human.
Short Label hRPS8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P62241 (RPS8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805
S4 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K24 Acetylation PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
K26 Sumoylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
Y27 Phosphorylation HPRD   PhosphoSitePlus 20068231
T36 Phosphorylation HPRD   PhosphoSitePlus 20068231
K37 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
C71 S-Nitrosylation dbSNO 26338901
C72 S-Nitrosylation dbSNO 26338901
T76 Phosphorylation PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
T93 Phosphorylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
C100 Methylation IEDB 31844290
C100 S-Nitrosylation dbSNO 2212679, 18335467, 22126794, ...22178444, 26338901, 19366988
S106 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
Y109 Phosphorylation PhosphoSitePlus
R110 Methylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
K128 Sumoylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
T130 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19664994, 19007248, ...18669648, 20068231
K139 Acetylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
K157 Sumoylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S160 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163
K170 Ubiquitination PhosphoSitePlus
C174 Methylation IEDB 31844290
R184 Methylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
R200 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
G2 D2 Biomuta DOID:363 / uterine cancer [ icgc ]
C71 W71 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
C72 Y72 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y83 C83 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y109 C109 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S159 N159 Biomuta DOID:1319 / brain cancer [ cosmic ]
C174 Y174 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R184 Q184 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y198 C198 Biomuta DOID:5041 / esophageal cancer [ cosmic ]