iPTMnet Report for P62191 (PSMC1)
Protein Information
UniProt AC / UniProt ID | P62191 / PRS4_HUMAN |
Protein Name | 26S proteasome regulatory subunit 4 |
Gene Name | Name: PSMC1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P62191 |
PRO Name | 26S proteasome regulatory subunit 4 (human) |
Definition | A 26S proteasome regulatory subunit 4 that is encoded in the genome of human. |
Short Label | hPSMC1 |
Category | organism-gene |
P62191 (PSMC1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
G2 | Myristoylation | score1 | UniProt | 22223895, 25255805, 25807930 | ||
S4 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
K24 | Acetylation | score1 | PhosphoSitePlus | |||
K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y25 | Phosphorylation | score1 | PhosphoSitePlus | |||
K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
T53 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
T56 | Phosphorylation | score1 | PhosphoSitePlus | |||
C58 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y71 | Phosphorylation | score1 | PhosphoSitePlus | |||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
K98 | Sumoylation | score1 | PhosphoSitePlus | |||
K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K175 | Sumoylation | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y210 | Phosphorylation | score1 | PhosphoSitePlus | |||
K217 | Ubiquitination | score1 | PhosphoSitePlus | |||
K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y225 | Phosphorylation | score1 | PhosphoSitePlus | |||
K232 | Ubiquitination | score1 | PhosphoSitePlus | |||
K237 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 17370265 | ||
T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K258 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K258 | Ubiquitination | score1 | PhosphoSitePlus | |||
K265 | Acetylation | score1 | PhosphoSitePlus | |||
K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
S297 | Phosphorylation | score1 | PhosphoSitePlus | |||
T308 | Phosphorylation | score1 | PhosphoSitePlus | |||
R322 | Methylation | score1 | PhosphoSitePlus | |||
K326 | Ubiquitination | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
S370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
K396 | Ubiquitination | score1 | PhosphoSitePlus | |||
C399 | Methylation | score1 | IEDB | 31844290 | ||
K413 | Ubiquitination | score1 | PhosphoSitePlus | |||
K420 | Acetylation | score1 | PhosphoSitePlus | |||
K420 | Ubiquitination | score1 | PhosphoSitePlus | |||
K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
K429 | Acetylation | score1 | PhosphoSitePlus | |||
K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
K430 | Sumoylation | score1 | PhosphoSitePlus | |||
K430 | Ubiquitination | score1 | PhosphoSitePlus | |||
T434 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y439 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15144186 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K48 | N48 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K61 | Q61 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
Y225 | C225 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K258 | R258 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T308 | A308 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K423 | N423 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |