iPTMnet Report P62070 RRAS2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P62070 / RRAS2_HUMAN
Protein Name	Ras-related protein R-Ras2 precursor
Gene Name	Name: RRAS2 Synonyms:TC21;
Organism	Homo sapiens (Human)

PRO ID	PR:P62070 DAG View
PRO Name	Ras-related protein R-Ras2 (human)
Definition	A Ras-related protein R-Ras2 that is encoded in the genome of human.
Short Label	hRRAS2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P62070 (RRAS2) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	A2	Acetylation		score1	UniProt	19413330
	S10	Phosphorylation		score1	PhosphoSitePlus
	Y15	Phosphorylation		score1	PhosphoSitePlus
	Y43	Phosphorylation		score1	PhosphoSitePlus
	C55	Methylation		score1	IEDB	31844290
	C55	S-Nitrosylation		score0	dbSNO	21278135
	Y105	Phosphorylation		score1	PhosphoSitePlus
	K128	Ubiquitination		score1	PhosphoSitePlus
	K177	Ubiquitination		score1	PhosphoSitePlus
	C183	S-Nitrosylation		score0	dbSNO	21278135
	S186	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18691976, 23186163, 17081983, ...19369195, 18669648, 24275569, 20068231
	T190	Phosphorylation		score1	PhosphoSitePlus
	K192	Ubiquitination		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S186	Phosphorylation		score0	HPRD	19413330, 18691976, 18578522, ...18767875, 19664994, 19664995, 17322306, 18669648, 20166139, 20068231
	T190	Phosphorylation		score0	HPRD	19413330, 20166139, 18578522, ...19664994

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
Y105	C105	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]
K177	T177	Biomuta		DOID:10534 / stomach cancer [ cosmic, icgc ]