iPTMnet Report for P61604 (HSPE1)
Protein Information
UniProt AC / UniProt ID | P61604 / CH10_HUMAN |
Protein Name | 10 kDa heat shock protein, mitochondrial |
Gene Name | Name: HSPE1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P61604 |
PRO Name | 10 kDa heat shock protein, mitochondrial (human) |
Definition | A 10 kDa heat shock protein, mitochondrial that is encoded in the genome of human. |
Short Label | hHSPE1 |
Category | organism-gene |
P61604 (HSPE1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | PRO | |||
K8 | Acetylation | score1 | PhosphoSitePlus | |||
K8 | Methylation | score1 | PhosphoSitePlus | |||
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
R15 | Methylation | score1 | PhosphoSitePlus | |||
S21 | O-Glycosylation | score1 | GlyGen | 20305658, 30444036, 31637018 | ||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
T27 | Phosphorylation | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
K36 | Methylation | score1 | PhosphoSitePlus | |||
K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
S37 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 34433824 | ||
K40 | Acetylation | score1 | PhosphoSitePlus | |||
K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
T45 | Phosphorylation | score1 | PhosphoSitePlus | |||
S51 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19415658 | ||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
K56 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
S64 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
K70 | Acetylation | score1 | PhosphoSitePlus | |||
K70 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
T79 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20068231 | ||
K80 | Acetylation | score1 | PhosphoSitePlus | |||
K80 | Sumoylation | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
K86 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y88 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18083107 | ||
R92 | Methylation | score1 | PhosphoSitePlus | |||
K99 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K99 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R15 | Q15 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T45 | R45 | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
S51 | L51 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S51 | W51 | Biomuta | DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ] |