iPTMnet Report for P61086 (UBE2K)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61086 / UBE2K_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 K
Gene Name Name: UBE2K
Synonyms:HIP2,LIG;
Organism Homo sapiens (Human)

PRO ID PR:P61086
DAG View
PRO Name ubiquitin-conjugating enzyme E2 K (human)
Definition A ubiquitin-conjugating enzyme E2 K that is encoded in the genome of human.
Short Label hUBE2K
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61086 (UBE2K) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K14 Acetylation PhosphoSitePlus   UniProt 19608861
K14 Sumoylation PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
K18 Methylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
R40 Methylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus   UniProt 23186163
K164 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K28 E28 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S159 T159 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K165 R165 Biomuta DOID:363 / uterine cancer [ icgc ]