iPTMnet Report for P61020 (RAB5B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61020 / RAB5B_HUMAN
Protein Name Ras-related protein Rab-5B
Gene Name Name: RAB5B
Organism Homo sapiens (Human)

PRO ID PR:P61020
DAG View
PRO Name Ras-related protein Rab-5B (human)
Definition A Ras-related protein Rab-5B that is encoded in the genome of human.
Short Label hRAB5B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61020 (RAB5B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Acetylation UniProt 19413330
T6 Phosphorylation Q5S007 (LRRK2) PhosphoSitePlus   RLIMS-P 25605758
K17 Ubiquitination PhosphoSitePlus
K22 Acetylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus   UniProt 29125462
K116 Ubiquitination PhosphoSitePlus
S123 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 10403367
S125 Phosphorylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S123 Phosphorylation P06493 (CDK1) HPRD 10403367


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K17 Q17 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S29 F29 Biomuta DOID:4159 / skin cancer [ cosmic ]
S84 C84 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K140 E140 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]