iPTMnet Report for P60900 (PSMA6)
Protein Information
UniProt AC / UniProt ID | P60900 / PSA6_HUMAN |
Protein Name | Proteasome subunit alpha type-6 |
Gene Name | Name: PSMA6 Synonyms:PROS27; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P60900 |
PRO Name | proteasome subunit alpha type-6 (human) |
Definition | A proteasome subunit alpha type-6 that is encoded in the genome of human. |
Short Label | hPSMA6 |
Category | organism-gene |
P60900 (PSMA6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R3 | Methylation | score1 | PhosphoSitePlus | |||
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
R11 | Methylation | score1 | PhosphoSitePlus | |||
T14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R21 | Methylation | score1 | PhosphoSitePlus | |||
Y23 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y27 | Phosphorylation | score1 | PhosphoSitePlus | |||
K30 | Methylation | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
K45 | Acetylation | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Acetylation | score1 | PhosphoSitePlus | |||
K55 | Sumoylation | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
K59 | Acetylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
S63 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S64 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T65 | Phosphorylation | score1 | PhosphoSitePlus | |||
K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
T73 | Phosphorylation | score1 | PhosphoSitePlus | |||
C78 | Methylation | score1 | IEDB | 31844290 | ||
Y96 | Phosphorylation | score1 | PhosphoSitePlus | |||
K102 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K102 | Methylation | score1 | PhosphoSitePlus | |||
K102 | Sumoylation | score1 | PhosphoSitePlus | |||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y103 | Phosphorylation | score1 | PhosphoSitePlus | |||
K104 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y105 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
K116 | Acetylation | score1 | PhosphoSitePlus | |||
K116 | Ubiquitination | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
C154 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
Y159 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y160 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
C161 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K181 | Acetylation | score1 | PhosphoSitePlus | |||
K181 | Ubiquitination | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
C201 | Methylation | score1 | IEDB | 31844290 | ||
K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
T231 | Phosphorylation | score1 | PhosphoSitePlus | |||
R245 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R3 | H3 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
R3 | C3 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R11 | C11 | Biomuta | DOID:10283 / prostate cancer [ icgc ] | |
K45 | E45 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S63 | F63 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K71 | N71 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T73 | N73 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K102 | N102 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K153 | E153 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K164 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K211 | E211 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R245 | T245 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
R245 | I245 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |