iPTMnet Report for P60660 (MYL6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P60660 / MYL6_HUMAN
Protein Name Myosin light polypeptide 6
Gene Name Name: MYL6
Organism Homo sapiens (Human)

PRO ID PR:P60660
DAG View
PRO Name myosin light polypeptide 6 (human)
Definition A myosin light polypeptide 6 that is encoded in the genome of human.
Short Label hMYL6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P60660 (MYL6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C2 Acetylation UniProt 19413330, 22814378, 22223895, ...25944712
K13 Ubiquitination PhosphoSitePlus
R21 Methylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
Y29 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S30 Phosphorylation PhosphoSitePlus
T44 Phosphorylation PhosphoSitePlus
K50 Acetylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K56 Sumoylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K63 Ubiquitination PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K81 Acetylation PhosphoSitePlus   UniProt 19608861
K81 Ubiquitination PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
R94 Methylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
T103 Phosphorylation PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus   UniProt 18669648
Y141 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y29 Phosphorylation HPRD 18083107
Y86 Phosphorylation HPRD 15592455
Y89 Phosphorylation HPRD 15592455
T103 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y29 Phosphorylation HPRD   PhosphoSitePlus 18083107
K50 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
Y86 Phosphorylation HPRD   PhosphoSitePlus 15592455
Y89 Phosphorylation HPRD   PhosphoSitePlus 15592455
T103 Phosphorylation HPRD 20068231
S135 Phosphorylation HPRD   PhosphoSitePlus 18669648, 20068231
Y141 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K13 * Biomuta DOID:1324 / lung cancer [ cosmic ]
R21 P21 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R21 Q21 Biomuta DOID:363 / uterine cancer [ cosmic ]
R94 W94 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R94 L94 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]