iPTMnet Report for P60510 (PPP4C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P60510 / PP4C_HUMAN
Protein Name Serine/threonine-protein phosphatase 4 catalytic subunit
Gene Name Name: PPP4C
Synonyms:PPP4,PPX;
Organism Homo sapiens (Human)

PRO ID PR:P60510
DAG View
PRO Name serine/threonine-protein phosphatase 4 catalytic subunit (human)
Definition A serine/threonine-protein phosphatase 4 catalytic subunit that is encoded in the genome of human.
Short Label hPPP4C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P60510 (PPP4C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
R15 Methylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
C29 Methylation IEDB 31844290
K31 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
C130 Methylation IEDB 31844290
K133 Ubiquitination PhosphoSitePlus
C162 Methylation IEDB 33981976, 31844290
K183 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K21 E21 Biomuta DOID:1324 / lung cancer [ cosmic ]
K31 N31 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R107 H107 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]