iPTMnet Report for P57087 (JAM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P57087 / JAM2_HUMAN
Protein Name Junctional adhesion molecule B precursor
Gene Name Name: JAM2
Synonyms:C21orf43;ORFNames:UNQ219/PRO245;
Organism Homo sapiens (Human)

PRO ID PR:P57087
DAG View
PRO Name junctional adhesion molecule B (human)
Definition A junctional adhesion molecule B that is encoded in the genome of human.
Short Label hJAM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P57087 (JAM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Acetylation PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
N98 N-Glycosylation GlyGen   UniProt 16335952
N187 N-Glycosylation GlyGen 24190977
S276 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S280 Phosphorylation phospho.ELM 12953056
S286 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S280 Phosphorylation HPRD 12953056


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K51 R51 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S278 Y278 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S286 N286 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K291 Q291 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]