iPTMnet Report for P56937 (HSD17B7)
Protein Information
UniProt AC / UniProt ID | P56937 / DHB7_HUMAN |
Protein Name | 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 |
Gene Name | Name: HSD17B7 Synonyms:17HSD7;ORFNames:UNQ2563/PRO6243; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P56937 |
PRO Name | 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (human) |
Definition | A 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 that is encoded in the genome of human. |
Short Label | hHSD17B7 |
Category | organism-gene |
P56937 (HSD17B7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
T125 | Phosphorylation | score1 | PhosphoSitePlus | |||
K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y198 | Phosphorylation | score1 | PhosphoSitePlus | |||
C222 | Methylation | score1 | IEDB | 31844290 | ||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y313 | Phosphorylation | score1 | PhosphoSitePlus | |||
K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
K321 | Acetylation | score1 | PhosphoSitePlus | |||
K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
S339 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K188 | E188 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K311 | N311 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K311 | Q311 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K321 | E321 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] |