iPTMnet Report for P56182 (RRP1)
Protein Information
UniProt AC / UniProt ID | P56182 / RRP1_HUMAN |
Protein Name | Ribosomal RNA processing protein 1 homolog A |
Gene Name | Name: RRP1 Synonyms:D21S2056E,NNP1,NOP52,RRP1A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P56182 |
PRO Name | ribosomal RNA processing protein 1 homolog A (human) |
Definition | A ribosomal RNA processing protein 1 homolog A that is encoded in the genome of human. |
Short Label | hRRP1 |
Category | organism-gene |
P56182 (RRP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
T24 | Phosphorylation | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
T204 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
T220 | Phosphorylation | score2 | HPRD phospho.ELM | 17081983 | ||
T238 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S245 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17081983, 24275569 | ||
S247 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 17081983 | ||
S250 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 21406692, 17081983 | ||
S251 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
S291 | Phosphorylation | score1 | PhosphoSitePlus | |||
K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
K347 | Ubiquitination | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 19007248, 19691289 | ||
S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
T412 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19007248, 20068231 | ||
R423 | Methylation | score1 | PhosphoSitePlus | |||
Q427 | Methylation | score1 | UniProt | 26797129 | ||
T436 | Phosphorylation | score1 | PhosphoSitePlus | |||
R444 | Methylation | score1 | PhosphoSitePlus | |||
K455 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K205 | N205 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T220 | A220 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S251 | Y251 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
S291 | N291 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K330 | T330 | Biomuta | DOID:363 / uterine cancer [ icgc ] |