Protein Information

Cytoscape View


UniProt AC / UniProt ID P55040 / GEM_HUMAN
Protein Name GTP-binding protein GEM
Gene Name Name: GEM
Synonyms:KIR;
Organism Homo sapiens (Human)

PRO ID PR:P55040
DAG View
PRO Name GTP-binding protein GEM (human)
Definition A GTP-binding protein GEM that is encoded in the genome of human.
Short Label hGEM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55040 (GEM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
C198 Methylation IEDB 31844290
Y255 Phosphorylation PhosphoSitePlus
S261 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 14701738
S261 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 14701738
K276 Acetylation PhosphoSitePlus
K279 Acetylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
S289 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 14701738


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 G23 Biomuta DOID:4159 / skin cancer [ cosmic ]
S57 R57 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S261 R261 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S289 F289 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]