iPTMnet Report for P55017 (SLC12A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55017 / S12A3_HUMAN
Protein Name Solute carrier family 12 member 3
Gene Name Name: SLC12A3
Synonyms:NCC;
Organism Homo sapiens (Human)

PRO ID PR:P55017
DAG View
PRO Name solute carrier family 12 member 3 (human)
Definition A solute carrier family 12 member 3 that is encoded in the genome of human.
Short Label hSLC12A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55017 (SLC12A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T46 Phosphorylation Q9UEW8 (STK39) , O95747 (OXSR1) neXtProt   PhosphoSitePlus   UniProt 18270262, 21423148, 20091762
T50 Phosphorylation PhosphoSitePlus
T55 Phosphorylation Q9UEW8 (STK39) , O95747 (OXSR1) neXtProt   PhosphoSitePlus   UniProt 18270262, 21423148, 20091762
T60 Phosphorylation Q9UEW8 (STK39) , O95747 (OXSR1) neXtProt   PhosphoSitePlus   Signor   UniProt 18270262, 21423148, 20091762
T66 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S73 Phosphorylation O95747 (OXSR1) PhosphoSitePlus 21423148
T74 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
S91 Phosphorylation Q9UEW8 (STK39) neXtProt   PhosphoSitePlus   UniProt 23186163, 18270262, 21423148, ...20091762
K94 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K140 Acetylation PhosphoSitePlus
N406 N-Glycosylation UniProt 36351028
N426 N-Glycosylation UniProt 36351028
Y605 Phosphorylation PhosphoSitePlus
T697 Phosphorylation PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
K734 Acetylation PhosphoSitePlus
K743 Acetylation PhosphoSitePlus
S783 Phosphorylation PhosphoSitePlus
K784 Ubiquitination PhosphoSitePlus
K801 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
K828 Ubiquitination PhosphoSitePlus
K885 Acetylation PhosphoSitePlus
K909 Ubiquitination PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
K940 Ubiquitination PhosphoSitePlus
K948 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S811 Phosphorylation PhosphoSitePlus
K819 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K94 Ubiquitination PhosphoSitePlus
K818 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T50 A50 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K81 R81 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S91 F91 Biomuta DOID:4159 / skin cancer [ cosmic ]
S91 Y91 Biomuta DOID:1324 / lung cancer [ cosmic ]
K706 R706 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K706 N706 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S783 Y783 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K784 M784 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K814 N814 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K940 N940 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]