iPTMnet Report for P54920 (NAPA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P54920 / SNAA_HUMAN
Protein Name Alpha-soluble NSF attachment protein
Gene Name Name: NAPA
Synonyms:SNAPA;
Organism Homo sapiens (Human)

PRO ID PR:P54920
DAG View
PRO Name alpha-soluble NSF attachment protein (human)
Definition An alpha-soluble NSF attachment protein that is encoded in the genome of human.
Short Label hNAPA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54920 (NAPA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K22 Ubiquitination PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus   UniProt 23186163
K56 Ubiquitination PhosphoSitePlus
C84 Methylation IEDB 31844290
K93 Acetylation PhosphoSitePlus
K94 Acetylation PhosphoSitePlus
C103 Methylation IEDB 31844290
Y111 Phosphorylation PhosphoSitePlus
S126 Phosphorylation PhosphoSitePlus
Y151 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus   UniProt 24275569
K199 Ubiquitination PhosphoSitePlus
K203 Acetylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
C241 Methylation IEDB 31844290
K246 Ubiquitination PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
T278 O-Glycosylation GlyGen 33214551, 30444036, 34019948, ...33465208
K285 Ubiquitination PhosphoSitePlus
R295 Methylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P46459 (NSF) Y83 P54920 (NAPA) inhibited_association eFIP 15322554


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K22 N22 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K22 Q22 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S24 W24 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S26 F26 Biomuta DOID:1612 / breast cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
K93 T93 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K264 M264 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]