iPTMnet Report for P54105 (CLNS1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P54105 / ICLN_HUMAN
Protein Name Methylosome subunit pICln
Gene Name Name: CLNS1A
Synonyms:CLCI,ICLN;
Organism Homo sapiens (Human)

PRO ID PR:P54105
DAG View
PRO Name methylosome subunit pICln (human)
Definition A methylosome subunit pICln that is encoded in the genome of human.
Short Label hCLNS1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P54105 (CLNS1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
R43 Methylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S67 O-Glycosylation GlyGen 23301498, 30379171, 34019948, ...33330510
C73 Methylation IEDB 31844290
K91 Ubiquitination PhosphoSitePlus
S102 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19562805, 18318008, 18691976, ...21406692, 23186163, 18212344, 20230923, 18452278, 17487921, 19690332, 19413330, 20058876, 19651622, 19369195, 18491316, 17287340, 17081983, 19664994, 19664995, 17322306, 18669648, 20166139, 19415658, 20068231
S144 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y147 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
S193 O-Glycosylation GlyGen 33330510
S193 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
S195 O-Glycosylation GlyGen 33330510
S195 Phosphorylation PhosphoSitePlus   UniProt 23186163
S197 O-Glycosylation GlyGen 33330510
S197 Phosphorylation PhosphoSitePlus
S198 O-Glycosylation GlyGen 33330510
S198 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y200 Phosphorylation PhosphoSitePlus
T207 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S210 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
R212 Methylation PhosphoSitePlus
Y214 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455, 16497976
T223 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R43 C43 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S175 F175 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S195 C195 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T223 A223 Biomuta DOID:363 / uterine cancer [ icgc ]