iPTMnet Report for P53985 (SLC16A1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P53985 / MOT1_HUMAN
Protein Name Monocarboxylate transporter 1
Gene Name Name: SLC16A1
Synonyms:MCT1;
Organism Homo sapiens (Human)

PRO ID PR:P53985
DAG View
PRO Name monocarboxylate transporter 1 (human)
Definition A monocarboxylate transporter 1 that is encoded in the genome of human.
Short Label hSLC16A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P53985 (SLC16A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S33 Phosphorylation PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
S213 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 20068231
K216 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
S461 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...19369195, 18669648
K462 Ubiquitination PhosphoSitePlus
T466 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...17081983
S467 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...24275569
K473 Ubiquitination PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
S483 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
K487 Ubiquitination PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
K494 Methylation PhosphoSitePlus
K494 Ubiquitination PhosphoSitePlus
S498 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18669648, 24275569, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S213 Phosphorylation HPRD 17081983, 20068231
S461 Phosphorylation HPRD 19413330, 18691976, 17081983, ...18452278, 19651622, 18669648, 18707149, 20166139, 20068231
T466 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19651622, 18452278, 17322306, 18669648, 20166139, 20068231
S467 Phosphorylation HPRD 19413330, 18691976, 18767875, ...19651622, 19691289, 18452278, 17322306, 18669648, 20166139, 20068231
S483 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S244 L244 Biomuta DOID:1324 / lung cancer [ cosmic ]
S483 C483 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]