iPTMnet Report for P53708 (ITGA8)
Protein Information
UniProt AC / UniProt ID | P53708 / ITA8_HUMAN |
Protein Name | Integrin alpha-8 precursor |
Gene Name | Name: ITGA8 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P53708 |
PRO Name | integrin alpha-8 (human) |
Definition | An integrin alpha-8 that is encoded in the genome of human. |
Short Label | hITGA8 |
Category | organism-gene |
P53708 (ITGA8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
S367 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S368 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
T378 | Phosphorylation | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y481 | Phosphorylation | score1 | PhosphoSitePlus | |||
K573 | Ubiquitination | score1 | PhosphoSitePlus | |||
K614 | Acetylation | score1 | PhosphoSitePlus | |||
K620 | Acetylation | score1 | PhosphoSitePlus | |||
K751 | Ubiquitination | score1 | PhosphoSitePlus | |||
K767 | Ubiquitination | score1 | PhosphoSitePlus | |||
K948 | Ubiquitination | score1 | PhosphoSitePlus | |||
T997 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S998 | O-Glycosylation | score1 | GlyGen | 29351928 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S72 | I72 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K418 | R418 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K767 | N767 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K767 | E767 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |