Protein Information

Cytoscape View


UniProt AC / UniProt ID P52952 / NKX25_HUMAN
Protein Name Homeobox protein Nkx-2.5
Gene Name Name: NKX2-5
Synonyms:CSX,NKX2.5,NKX2E;
Organism Homo sapiens (Human)

PRO ID PR:P52952
DAG View
PRO Name homeobox protein Nkx-2.5 (human)
Definition A homeobox protein Nkx-2.5 that is encoded in the genome of human.
Short Label hNKX2-5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52952 (NKX2-5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S78 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
T180 Phosphorylation PhosphoSitePlus
R225 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S164 Phosphorylation HPRD 9858576
S164 Phosphorylation P68400 (CSNK2A1) HPRD 9858576
Site PTM Type PTM Enzyme Score Source PMID
S139 Phosphorylation PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T180 M180 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R225 S225 Biomuta DOID:1324 / lung cancer [ cosmic ]