iPTMnet Report for P52756 (RBM5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P52756 / RBM5_HUMAN
Protein Name RNA-binding protein 5
Gene Name Name: RBM5
ORFNames:H37,LUCA15;
Organism Homo sapiens (Human)

PRO ID PR:P52756
DAG View
PRO Name RNA-binding protein 5 (human)
Definition An RNA-binding protein 5 that is encoded in the genome of human.
Short Label hRBM5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52756 (RBM5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
T10 Phosphorylation PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus   UniProt 23186163
S37 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
Y54 Phosphorylation PhosphoSitePlus
Y57 Phosphorylation PhosphoSitePlus
S59 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S69 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 16927403, 23186163, 17081983
S72 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y76 Phosphorylation PhosphoSitePlus
S78 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
Y82 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus   UniProt 24275569
K542 Acetylation PhosphoSitePlus
K549 Acetylation PhosphoSitePlus
K553 Acetylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
Y620 Phosphorylation PhosphoSitePlus
S621 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 17081983
S624 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18220336, 18669648, 24275569, 19690332, 20068231
S636 Phosphorylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
Y712 Phosphorylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
Y733 Phosphorylation PhosphoSitePlus
K765 Sumoylation PhosphoSitePlus
T770 Phosphorylation PhosphoSitePlus
R778 Methylation PhosphoSitePlus
K780 Methylation PhosphoSitePlus
K787 Methylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
Y791 Phosphorylation PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
T812 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation HPRD 20068231
T10 Phosphorylation HPRD 20068231
S59 Phosphorylation HPRD 19651622, 18669648, 17081983, ...18452278
S69 Phosphorylation HPRD 17081983
S72 Phosphorylation HPRD 17081983
Y76 Phosphorylation HPRD 17081983
S78 Phosphorylation HPRD 18452278
Y620 Phosphorylation HPRD 17081983
S621 Phosphorylation HPRD 18691976, 18669648, 17081983, ...20068231, 18452278
S624 Phosphorylation HPRD 19413330, 18691976, 17081983, ...20058876, 19664994, 19664995, 18452278, 19651622, 18669648, 19415658, 20068231
S636 Phosphorylation HPRD 18452278
S669 Phosphorylation HPRD 20068231
Y712 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y54 C54 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y54 D54 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y54 H54 Biomuta DOID:363 / uterine cancer [ icgc ]
S69 I69 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S112 N112 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S112 C112 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S576 F576 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S669 L669 Biomuta DOID:4159 / skin cancer [ cosmic ]
T770 K770 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y791 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S794 L794 Biomuta [ cosmic ]
K800 R800 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]