iPTMnet Report for P52732 (KIF11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P52732 / KIF11_HUMAN
Protein Name Kinesin-like protein KIF11
Gene Name Name: KIF11
Synonyms:EG5,KNSL1,TRIP5;
Organism Homo sapiens (Human)

PRO ID PR:P52732
DAG View
PRO Name kinesin-like protein KIF11 (human)
Definition A kinesin-like protein KIF11 that is encoded in the genome of human.
Short Label hKIF11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52732 (KIF11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
S62 Phosphorylation HPRD 17081983
M95 Methylation IEDB 25880248
T114 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus   RLIMS-P 28646493
T126 Phosphorylation PhosphoSitePlus
K146 Acetylation PhosphoSitePlus   UniProt 19608861
K197 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus   RLIMS-P 28646493
K216 Ubiquitination PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 20166139, 28646493
S232 Phosphorylation HPRD   PhosphoSitePlus 20166139
S233 Phosphorylation HPRD   PhosphoSitePlus 20166139
S240 Phosphorylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
S275 Phosphorylation IEDB 35494241
S291 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K372 Acetylation PhosphoSitePlus
K376 Acetylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
Y399 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
T458 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 19691289
T463 Phosphorylation PhosphoSitePlus
T464 Phosphorylation PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
Y480 Phosphorylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
T506 Phosphorylation HPRD 20068231
T507 Phosphorylation HPRD   PhosphoSitePlus 20068231
K508 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
T643 Phosphorylation PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
K659 Ubiquitination PhosphoSitePlus
T663 Phosphorylation PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
C683 Methylation IEDB 31844290
C695 Methylation IEDB 31844290
K712 Ubiquitination PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
C723 Methylation IEDB 31844290
K724 Ubiquitination PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
K764 Ubiquitination PhosphoSitePlus
K771 Acetylation PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
R784 Methylation PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
K803 Ubiquitination PhosphoSitePlus
K810 Ubiquitination PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
S858 Phosphorylation PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
K890 Ubiquitination PhosphoSitePlus
K908 Ubiquitination PhosphoSitePlus
K918 Ubiquitination PhosphoSitePlus
T923 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18767875, 19691289, 17322306, ...18669648, 20068231
T925 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19664995, ...19691289, 18669648, 20068231
T926 Phosphorylation P06493 (CDK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19413330, 19001501, 23186163, ...8548803, 19664994, 32873777, 19691289, 9235942, 27492783, 28487562, 19007248, 16565220, 20068231, 20068230
K930 Ubiquitination PhosphoSitePlus
S931 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19691289, 20068231, 16565220
Y932 Phosphorylation PhosphoSitePlus
Y934 Phosphorylation PhosphoSitePlus
S936 Phosphorylation PhosphoSitePlus
K952 Ubiquitination PhosphoSitePlus
R1025 Methylation PhosphoSitePlus
T1029 Phosphorylation HPRD   PhosphoSitePlus 19007248
S1033 Phosphorylation Q9HC98 (NEK6) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 19001501, 23186163, 19007248, ...29899413, 35977011
K1034 Ubiquitination PhosphoSitePlus
K1045 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T926 Phosphorylation PRO 19001501


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036626 (hKIF11/iso:1/Phos:1) pT926 PRO 19001501


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K357 N357 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y399 C399 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ]
T643 I643 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C695 Y695 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R784 K784 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]