iPTMnet Report for P52566 (ARHGDIB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P52566 / GDIR2_HUMAN
Protein Name Rho GDP-dissociation inhibitor 2
Gene Name Name: ARHGDIB
Synonyms:GDIA2,GDID4,RAP1GN1;
Organism Homo sapiens (Human)

PRO ID PR:P52566
DAG View
PRO Name Rho GDP-dissociation inhibitor 2 (human)
Definition A Rho GDP-dissociation inhibitor 2 that is encoded in the genome of human.
Short Label hARHGDIB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P52566 (ARHGDIB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Acetylation IEDB   PhosphoSitePlus 34433824
K4 Ubiquitination PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus   UniProt 19608861
K21 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation P12931 (SRC) , P43405 (SYK) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15592455, 32903764, 19321744, ...24055812
K25 Acetylation PhosphoSitePlus   UniProt 19608861
K25 Ubiquitination PhosphoSitePlus
K30 Acetylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
S31 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   RLIMS-P   Signor 22469974
K33 Acetylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K40 Acetylation PhosphoSitePlus   UniProt 19608861
K40 Ubiquitination PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus   UniProt 19608861
K47 Ubiquitination PhosphoSitePlus
Y48 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
T51 Phosphorylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
T70 O-Glycosylation GlyGen 30379171, 29351928
T73 O-Glycosylation GlyGen 30379171, 29351928
C76 S-Nitrosylation dbSNO 25040305
S78 Phosphorylation PhosphoSitePlus
K95 Acetylation PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K102 Acetylation PhosphoSitePlus   UniProt 19608861
K102 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K124 Acetylation PhosphoSitePlus   UniProt 19608861
K124 Ubiquitination PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus   RLIMS-P 32903764
K135 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus   UniProt 19690332
Y146 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P   Signor 32903764, 19321744
T157 Phosphorylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K175 Acetylation PhosphoSitePlus   UniProt 19608861
K175 Ubiquitination PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
K197 Acetylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P52566 (ARHGDIB) S31 P63000 (RAC1) inhibited_association eFIP 22469974