iPTMnet Report P51674 GPM6A

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P51674 / GPM6A_HUMAN
Protein Name	Neuronal membrane glycoprotein M6-a
Gene Name	Name: GPM6A Synonyms:M6A;
Organism	Homo sapiens (Human)

PRO ID	PR:P51674 DAG View
PRO Name	neuronal membrane glycoprotein M6-a (human)
Definition	A neuronal membrane glycoprotein M6-a that is encoded in the genome of human.
Short Label	hGPM6A
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P51674 (GPM6A) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	UniProt	22223895
	T10	Phosphorylation		score2	phospho.ELM	12359212
	Y251	Phosphorylation		score1	PhosphoSitePlus
	S256	Phosphorylation		score1	PhosphoSitePlus
	K257	Ubiquitination		score1	PhosphoSitePlus
	S267	Phosphorylation		score1	PhosphoSitePlus
	Y277	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T10	Phosphorylation		score1	HPRD	12359212
	T10	Phosphorylation	P17252 (PRKCA)	score1	HPRD	12359212
	S256	Phosphorylation		score0	HPRD	18510355

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S245	Phosphorylation		score0	HPRD	18510355

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S245	L245	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]
S256	L256	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]
K257	*	Biomuta		DOID:5041 / esophageal cancer [ cosmic ]
S267	C267	Biomuta		DOID:1324 / lung cancer [ cosmic ]