iPTMnet Report for P51659 (HSD17B4)
Protein Information
UniProt AC / UniProt ID | P51659 / DHB4_HUMAN |
Protein Name | Peroxisomal multifunctional enzyme type 2 |
Gene Name | Name: HSD17B4 Synonyms:EDH17B4,SDR8C1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51659 |
PRO Name | peroxisomal multifunctional enzyme type 2 (human) |
Definition | A peroxisomal multifunctional enzyme type 2 that is encoded in the genome of human. |
Short Label | hHSD17B4 |
Category | organism-gene |
P51659 (HSD17B4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
K46 | Acetylation | score1 | PhosphoSitePlus | |||
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
S52 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K57 | Acetylation | score1 | PhosphoSitePlus | |||
K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
K81 | Acetylation | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
S112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K139 | Acetylation | score1 | PhosphoSitePlus | |||
Y143 | Phosphorylation | score1 | PhosphoSitePlus | |||
T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
S151 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y156 | Phosphorylation | score1 | PhosphoSitePlus | |||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
T265 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K270 | Acetylation | score1 | PhosphoSitePlus | |||
K270 | Ubiquitination | score1 | PhosphoSitePlus | |||
K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
S304 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
S309 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
T313 | Phosphorylation | score1 | PhosphoSitePlus | |||
T317 | Phosphorylation | score1 | PhosphoSitePlus | |||
S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
T319 | Phosphorylation | score1 | PhosphoSitePlus | |||
S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y347 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y414 | Phosphorylation | score1 | PhosphoSitePlus | |||
K415 | Acetylation | score1 | PhosphoSitePlus | |||
K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
C455 | Methylation | score1 | IEDB | 31844290 | ||
T474 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
S475 | O-Glycosylation | score1 | GlyGen | 32119511, 28510447, 34725712, ... | ||
C535 | Methylation | score1 | IEDB | 31844290 | ||
K565 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K565 | Ubiquitination | score1 | PhosphoSitePlus | |||
K579 | Acetylation | score1 | PhosphoSitePlus | |||
Y602 | Phosphorylation | score1 | PhosphoSitePlus | |||
K621 | Acetylation | score1 | PhosphoSitePlus | |||
K636 | Acetylation | score1 | PhosphoSitePlus | |||
K636 | Ubiquitination | score1 | PhosphoSitePlus | |||
K644 | Acetylation | score1 | PhosphoSitePlus | |||
T655 | Phosphorylation | score1 | PhosphoSitePlus | |||
T665 | O-Glycosylation | score1 | GlyGen | 32119511, 28510447, 34725712, ... | ||
K669 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K674 | Ubiquitination | score1 | PhosphoSitePlus | |||
K707 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K707 | Ubiquitination | score1 | PhosphoSitePlus | |||
S711 | Phosphorylation | score1 | PhosphoSitePlus | |||
K731 | Acetylation | score1 | PhosphoSitePlus | |||
K731 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | L3 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
S52 | F52 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K57 | M57 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S304 | * | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S304 | L304 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] | |
T317 | M317 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
C535 | F535 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K565 | N565 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K644 | N644 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
T655 | A655 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K674 | N674 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |