iPTMnet Report for P51636 (CAV2)
Protein Information
UniProt AC / UniProt ID | P51636 / CAV2_HUMAN |
Protein Name | Caveolin-2 |
Gene Name | Name: CAV2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51636 |
PRO Name | caveolin-2 (human) |
Definition | A caveolin-2 that is encoded in the genome of human. |
Short Label | hCAV2 |
Category | organism-gene |
P51636 (CAV2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
Y19 | Phosphorylation | P12931 (SRC) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 20455999, 25753664, 18669648, ... | |
S20 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S23 | Phosphorylation | P68400 (CSNK2A1) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 17081983, 18669648, 18081315, ... | |
Y27 | Phosphorylation | P12931 (SRC) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 15504032, 18669648, 25667086, ... | |
S36 | Phosphorylation | P68400 (CSNK2A1) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 17081983, 18081315, 12743374 | |
K50 | Ubiquitination | score1 | PhosphoSitePlus | |||
T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
C122 | Methylation | score1 | IEDB | 31844290 | ||
S128 | Phosphorylation | score1 | PhosphoSitePlus | |||
T131 | Phosphorylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
S154 | Phosphorylation | score0 | RLIMS-P | 20455999 | ||
S156 | Phosphorylation | score0 | RLIMS-P | 20455999 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S18 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
Y19 | Phosphorylation | P12931 (SRC) | score2 | HPRD | 12091389, 18669648, 20068231 | |
S20 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 17081983, ... | ||
S23 | Phosphorylation | score2 | HPRD | 20166139, 18669648, 12743374 | ||
Y27 | Phosphorylation | score2 | HPRD | 15504032, 18669648, 20068231 | ||
S36 | Phosphorylation | score1 | HPRD | 12743374 | ||
T121 | Phosphorylation | score0 | HPRD | 20068231 | ||
S128 | Phosphorylation | score0 | HPRD | 20068231 | ||
T131 | Phosphorylation | score0 | HPRD | 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S18 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
Y19 | Phosphorylation | P12931 (SRC) | score2 | HPRD | 12091389, 18669648, 20068231 | |
S20 | Phosphorylation | score0 | HPRD | 20166139, 18669648, 17081983, ... | ||
S23 | Phosphorylation | score2 | HPRD | 20166139, 18669648, 12743374 | ||
Y27 | Phosphorylation | score2 | HPRD | 15504032, 18669648, 20068231 | ||
S36 | Phosphorylation | score1 | HPRD | 12743374 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P51636 (CAV2) | Y19 | P28482 (MAPK1) | unknown | eFIP | 19778377 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y27 | S27 | Biomuta | DOID:4159 / skin cancer [ cosmic, cosmic ] | |
T121 | A121 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |