iPTMnet Report for P51575 (P2RX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51575 / P2RX1_HUMAN
Protein Name P2X purinoceptor 1
Gene Name Name: P2RX1
Synonyms:P2X1;
Organism Homo sapiens (Human)

PRO ID PR:P51575
DAG View
PRO Name P2X purinoceptor 1 (human)
Definition A P2X purinoceptor 1 that is encoded in the genome of human.
Short Label hP2RX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51575 (P2RX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y16 Phosphorylation RLIMS-P 22971236
T18 Phosphorylation RLIMS-P 22971236
S130 Phosphorylation PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
N153 N-Glycosylation GlyGen 23090970, 16371009
N184 N-Glycosylation GlyGen 23090970, 16371009
N242 N-Glycosylation GlyGen 16371009
Y274 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
Y370 Phosphorylation PhosphoSitePlus   RLIMS-P 22971236
T386 Phosphorylation RLIMS-P 22971236
S387 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 22971236
S388 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 22971236
T389 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 22971236
T398 Phosphorylation RLIMS-P 22971236
S399 Phosphorylation RLIMS-P 22971236


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S130 N130 Biomuta DOID:4159 / skin cancer [ cosmic ]
K138 R138 Biomuta DOID:4159 / skin cancer [ cosmic ]
N242 S242 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S399 C399 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S399 Y399 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]