iPTMnet Report for P51575 (P2RX1)
Protein Information
UniProt AC / UniProt ID | P51575 / P2RX1_HUMAN |
Protein Name | P2X purinoceptor 1 |
Gene Name | Name: P2RX1 Synonyms:P2X1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P51575 |
PRO Name | P2X purinoceptor 1 (human) |
Definition | A P2X purinoceptor 1 that is encoded in the genome of human. |
Short Label | hP2RX1 |
Category | organism-gene |
P51575 (P2RX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y16 | Phosphorylation | score0 | RLIMS-P | 22971236 | ||
T18 | Phosphorylation | score0 | RLIMS-P | 22971236 | ||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Acetylation | score1 | PhosphoSitePlus | |||
N153 | N-Glycosylation | score3 | GlyGen | 23090970, 16371009 | ||
N184 | N-Glycosylation | score3 | GlyGen | 23090970, 16371009 | ||
N242 | N-Glycosylation | score2 | GlyGen | 16371009 | ||
Y274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S286 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y370 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 22971236 | ||
T386 | Phosphorylation | score0 | RLIMS-P | 22971236 | ||
S387 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 22971236 | ||
S388 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 22971236 | ||
T389 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 22971236 | ||
T398 | Phosphorylation | score0 | RLIMS-P | 22971236 | ||
S399 | Phosphorylation | score0 | RLIMS-P | 22971236 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S130 | N130 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K138 | R138 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
N242 | S242 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S399 | C399 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S399 | Y399 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |