Protein Information

Cytoscape View


UniProt AC / UniProt ID P51397 / DAP1_HUMAN
Protein Name Death-associated protein 1
Gene Name Name: DAP
Synonyms:DAP1;
Organism Homo sapiens (Human)

PRO ID PR:P51397
DAG View
PRO Name death-associated protein 1 (human)
Definition A death-associated protein 1 that is encoded in the genome of human.
Short Label hDAP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51397 (DAP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 16602700
S2 Phosphorylation HPRD   PhosphoSitePlus 20068231
S3 Phosphorylation P42345 (MTOR) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20537536, 19413330, 16602700, ...20068231
K8 Ubiquitination PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
S49 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 16602700, 17322306, ...18669648, 20068231
S51 Phosphorylation P42345 (MTOR) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19651622, 21406692, 16602700, ...20537536, 17322306, 18669648, 20068231
K54 Ubiquitination PhosphoSitePlus
T56 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231
S60 Phosphorylation HPRD 17322306
K68 Acetylation PhosphoSitePlus
K81 Acetylation PhosphoSitePlus
S85 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S91 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340, 20068231
R93 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K20 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S51 G51 Biomuta DOID:3571 / liver cancer [ cosmic ]
S85 C85 Biomuta DOID:1319 / brain cancer [ cosmic ]
R93 T93 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]