iPTMnet Report for P51168 (SCNN1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P51168 / SCNNB_HUMAN
Protein Name Amiloride-sensitive sodium channel subunit beta
Gene Name Name: SCNN1B
Organism Homo sapiens (Human)

PRO ID PR:P51168
DAG View
PRO Name amiloride-sensitive sodium channel subunit beta (human)
Definition An amiloride-sensitive sodium channel subunit beta that is encoded in the genome of human.
Short Label hSCNN1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P51168 (SCNN1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Ubiquitination PhosphoSitePlus
N135 N-Glycosylation GlyGen 24190977
K182 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
N449 N-Glycosylation GlyGen 24190977
N484 N-Glycosylation GlyGen 24190977
S488 Phosphorylation PhosphoSitePlus
Y498 Phosphorylation PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
T615 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) neXtProt   PhosphoSitePlus   RLIMS-P 11805112, 28588583


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K16 N16 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N484 H484 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y498 C498 Biomuta DOID:1324 / lung cancer [ cosmic ]