iPTMnet Report for P50395 (GDI2)
Protein Information
UniProt AC / UniProt ID | P50395 / GDIB_HUMAN |
Protein Name | Rab GDP dissociation inhibitor beta |
Gene Name | Name: GDI2 Synonyms:RABGDIB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P50395 |
PRO Name | Rab GDP dissociation inhibitor beta (human) |
Definition | A Rab GDP dissociation inhibitor beta that is encoded in the genome of human. |
Short Label | hGDI2 |
Category | organism-gene |
P50395 (GDI2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
Y5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
R35 | Methylation | score1 | PhosphoSitePlus | |||
Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y53 | Phosphorylation | score1 | PhosphoSitePlus | |||
K54 | Acetylation | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
S61 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231 | ||
R68 | Methylation | score1 | PhosphoSitePlus | |||
R70 | Methylation | score1 | PhosphoSitePlus | |||
K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
T94 | Phosphorylation | score1 | PhosphoSitePlus | |||
T105 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
S108 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
Y111 | Phosphorylation | score1 | PhosphoSitePlus | |||
K112 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K112 | Methylation | score1 | PhosphoSitePlus | |||
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y117 | Phosphorylation | score1 | PhosphoSitePlus | |||
S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
T122 | Phosphorylation | score1 | PhosphoSitePlus | |||
K142 | Acetylation | score1 | PhosphoSitePlus | |||
K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
K153 | Acetylation | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
K164 | Acetylation | score1 | PhosphoSitePlus | |||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
K174 | Acetylation | score1 | PhosphoSitePlus | |||
K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
C202 | Methylation | score1 | IEDB | 31844290 | ||
Y203 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107, 16497976 | ||
T205 | Phosphorylation | score1 | PhosphoSitePlus | |||
K210 | Acetylation | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y212 | Phosphorylation | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
K221 | Acetylation | score1 | PhosphoSitePlus | |||
K221 | Methylation | score1 | PhosphoSitePlus | |||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
S222 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y224 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y226 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y229 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y245 | Phosphorylation | score1 | PhosphoSitePlus | |||
T248 | Phosphorylation | score1 | PhosphoSitePlus | |||
K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
K269 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K269 | Sumoylation | score1 | PhosphoSitePlus | |||
K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
S285 | Phosphorylation | score1 | PhosphoSitePlus | |||
K288 | Acetylation | score1 | PhosphoSitePlus | |||
K288 | Ubiquitination | score1 | PhosphoSitePlus | |||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
S305 | Phosphorylation | score1 | PhosphoSitePlus | |||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
S316 | Phosphorylation | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
S330 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y333 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y349 | Phosphorylation | score1 | PhosphoSitePlus | |||
T355 | Phosphorylation | score1 | PhosphoSitePlus | |||
K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
K364 | Acetylation | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
S382 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
K390 | Ubiquitination | score1 | PhosphoSitePlus | |||
T394 | Phosphorylation | score1 | PhosphoSitePlus | |||
S396 | Phosphorylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
T425 | Phosphorylation | score1 | PhosphoSitePlus | |||
S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
K435 | Acetylation | score1 | PhosphoSitePlus | |||
K435 | Ubiquitination | score1 | PhosphoSitePlus | |||
K438 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y442 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K29 | E29 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
R35 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
Y53 | C53 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K164 | R164 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
C202 | Y202 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
Y203 | C203 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K253 | N253 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y349 | C349 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S401 | P401 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |