Protein Information

Cytoscape View


UniProt AC / UniProt ID P49961 / ENTP1_HUMAN
Protein Name Ectonucleoside triphosphate diphosphohydrolase 1
Gene Name Name: ENTPD1
Synonyms:CD39;
Organism Homo sapiens (Human)

PRO ID PR:P49961
DAG View
PRO Name ectonucleoside triphosphate diphosphohydrolase 1 (human)
Definition An ectonucleoside triphosphate diphosphohydrolase 1 that is encoded in the genome of human.
Short Label hENTPD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49961 (ENTPD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y49 Phosphorylation PhosphoSitePlus
Y65 Phosphorylation PhosphoSitePlus
N73 N-Glycosylation GlyGen   UniProt 19159218, 24190977
C255 Methylation IEDB 31844290
N292 N-Glycosylation GlyGen   UniProt 19159218, 24190977
C301 Methylation IEDB 31844290
C325 Methylation IEDB 31844290
N371 N-Glycosylation GlyGen 29741879, 24190977
Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T4 A4 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
N292 K292 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
C301 R301 Biomuta DOID:1324 / lung cancer [ cosmic ]
C325 Y325 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]