iPTMnet Report for P49773 (HINT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49773 / HINT1_HUMAN
Protein Name Adenosine 5'-monophosphoramidase HINT1
Gene Name Name: HINT1
Synonyms:HINT,PKCI1,PRKCNH1;
Organism Homo sapiens (Human)

PRO ID PR:P49773
DAG View
PRO Name adenosine 5'-monophosphoramidase HINT1 (human)
Definition An adenosine 5'-monophosphoramidase HINT1 that is encoded in the genome of human.
Short Label hHINT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49773 (HINT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K7 Acetylation IEDB   PhosphoSitePlus 34357683
K7 Ubiquitination PhosphoSitePlus
K21 Acetylation PhosphoSitePlus   UniProt 19608861
K21 Methylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K30 Acetylation PhosphoSitePlus   UniProt 19608861
K30 Ubiquitination PhosphoSitePlus
R37 Methylation PhosphoSitePlus
C38 Methylation IEDB 31844290
S45 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
Y109 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R37 L37 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K58 T58 Biomuta DOID:363 / uterine cancer [ icgc ]
S72 I72 Biomuta DOID:1319 / brain cancer [ cosmic ]
K83 R83 Biomuta DOID:363 / uterine cancer [ icgc ]
Y94 C94 Biomuta DOID:9256 / colorectal cancer [ cosmic ]