iPTMnet Report for P49756 (RBM25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49756 / RBM25_HUMAN
Protein Name RNA-binding protein 25
Gene Name Name: RBM25
Synonyms:RNPC7;
Organism Homo sapiens (Human)

PRO ID PR:P49756
DAG View
PRO Name RNA-binding protein 25 (human)
Definition An RNA-binding protein 25 that is encoded in the genome of human.
Short Label hRBM25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49756 (RBM25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S45 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...35138101, 30397120, 32522876, 34019948, 32119511, 35289036, 28510447
T57 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...35138101, 30397120, 32522876, 34019948, 32119511, 35289036, 28510447
S59 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...35138101, 30397120, 32522876, 34019948, 32119511, 35289036, 28510447
K63 Acetylation PhosphoSitePlus
K77 Methylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
K135 Acetylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K173 Methylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
T189 Phosphorylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
Y218 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus   UniProt 23186163
S229 Phosphorylation PhosphoSitePlus   UniProt 23186163
S231 Phosphorylation PhosphoSitePlus
Y256 Phosphorylation PhosphoSitePlus
K261 Acetylation PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K283 Acetylation PhosphoSitePlus
T354 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K511 Ubiquitination PhosphoSitePlus
R514 Methylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K578 Sumoylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S653 Phosphorylation IEDB 32387766
S669 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...24275569, 19690332, 20068231
S683 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...20068231
K685 Ubiquitination PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
K697 Ubiquitination PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
K711 Ubiquitination PhosphoSitePlus
Y717 Phosphorylation PhosphoSitePlus
K722 Sumoylation PhosphoSitePlus
K726 Ubiquitination PhosphoSitePlus
T728 Phosphorylation PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
K749 Acetylation PhosphoSitePlus
Y832 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S231 Phosphorylation HPRD 18669648
S388 Phosphorylation HPRD 20068231
S516 Phosphorylation HPRD 20068231
S583 Phosphorylation HPRD 19413330, 19651622, 19691289, ...20068231, 18452278
S675 Phosphorylation HPRD 19413330, 17322306, 18767875, ...20058876, 19664995, 19651622, 18669648, 20068231
S677 Phosphorylation HPRD 19413330, 19664995, 17287340, ...18212344, 16964243, 18767875, 19664994, 19691289, 19007248, 19651622, 17322306, 18669648, 20058876, 20166139, 17924679, 19415658, 20068231, 20068230
S683 Phosphorylation HPRD 19413330, 16964243, 19664995, ...18669648, 20068231, 17924679
S693 Phosphorylation HPRD 20068231, 18452278
S703 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S45 N45 Biomuta DOID:363 / uterine cancer [ icgc ]
K125 N125 Biomuta DOID:1319 / brain cancer [ cosmic ]
K135 N135 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y218 S218 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S231 F231 Biomuta DOID:1324 / lung cancer [ cosmic ]
S382 R382 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y457 H457 Biomuta DOID:4159 / skin cancer [ cosmic ]
S669 R669 Biomuta DOID:363 / uterine cancer [ icgc ]
S675 C675 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S683 F683 Biomuta DOID:4159 / skin cancer [ cosmic ]
K697 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K722 T722 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K726 E726 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]