iPTMnet Report for P49750 (YLPM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P49750 / YLPM1_HUMAN
Protein Name YLP motif-containing protein 1
Gene Name Name: YLPM1
Synonyms:C14orf170,ZAP3;
Organism Homo sapiens (Human)

PRO ID PR:P49750
DAG View
PRO Name YLP motif-containing protein 1 (human)
Definition A YLP motif-containing protein 1 that is encoded in the genome of human.
Short Label hYLPM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P49750 (YLPM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
S206 O-Glycosylation GlyGen 27655845, 33214551, 35138101, ...35254053, 30379171, 34725712, 34019948, 30059200, 35132862, 31492838, 20305658, 32119511, 35289036, 29351928
S227 O-Glycosylation GlyGen 27655845, 33214551, 35138101, ...35254053, 30379171, 34725712, 34019948, 30059200, 35132862, 31492838, 20305658, 32119511, 35289036, 29351928
S228 O-Glycosylation GlyGen 27655845, 33214551, 35138101, ...35254053, 30379171, 34725712, 34019948, 30059200, 35132862, 31492838, 20305658, 32119511, 35289036, 29351928
S231 O-Glycosylation GlyGen 27655845, 33214551, 35138101, ...35254053, 30379171, 34725712, 34019948, 30059200, 35132862, 31492838, 20305658, 32119511, 35289036, 29351928
S236 O-Glycosylation GlyGen 27655845, 33214551, 35138101, ...35254053, 30379171, 34725712, 34019948, 30059200, 35132862, 31492838, 20305658, 32119511, 35289036, 29351928
S251 Phosphorylation PhosphoSitePlus
K317 Acetylation PhosphoSitePlus
K318 Acetylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
T326 Phosphorylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
S676 O-Glycosylation GlyGen 29351928
S713 Phosphorylation PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
K735 Acetylation PhosphoSitePlus
K735 Methylation PhosphoSitePlus   UniProt 24129315
R750 Methylation PhosphoSitePlus
S751 O-Glycosylation GlyGen 34846842
S752 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus   UniProt 23186163
R758 Methylation PhosphoSitePlus
R761 Methylation PhosphoSitePlus
R766 Methylation PhosphoSitePlus
R767 Methylation PhosphoSitePlus
R774 Methylation PhosphoSitePlus
R779 Methylation PhosphoSitePlus
K781 Methylation PhosphoSitePlus
R784 Methylation PhosphoSitePlus
R789 Methylation PhosphoSitePlus
R794 Methylation PhosphoSitePlus
R796 Methylation PhosphoSitePlus
Y797 Phosphorylation PhosphoSitePlus
K808 Methylation PhosphoSitePlus
R814 Methylation PhosphoSitePlus   UniProt 24129315
Y821 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
T826 Phosphorylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
S829 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...19690332, 20068231
R831 Methylation PhosphoSitePlus   UniProt 24129315
K838 Methylation PhosphoSitePlus
K841 Ubiquitination PhosphoSitePlus
S860 Phosphorylation PhosphoSitePlus
S870 Phosphorylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
K875 Acetylation PhosphoSitePlus
K875 Ubiquitination PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus
T942 O-Glycosylation GlyGen 32938750
K983 Sumoylation PhosphoSitePlus
R1014 Methylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
Y1020 Phosphorylation PhosphoSitePlus
S1026 Phosphorylation PhosphoSitePlus
R1041 Methylation PhosphoSitePlus
K1053 Methylation PhosphoSitePlus
K1053 Sumoylation PhosphoSitePlus
R1081 Methylation PhosphoSitePlus
R1085 Methylation PhosphoSitePlus
S1088 Phosphorylation PhosphoSitePlus
S1089 Phosphorylation PhosphoSitePlus
S1100 Phosphorylation PhosphoSitePlus   UniProt 23186163
R1103 Methylation PhosphoSitePlus
S1119 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S1130 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
R1144 Methylation PhosphoSitePlus
R1148 Methylation PhosphoSitePlus
S1152 Phosphorylation PhosphoSitePlus
R1153 Methylation PhosphoSitePlus
R1155 Methylation PhosphoSitePlus
R1159 Methylation PhosphoSitePlus
T1238 Phosphorylation PhosphoSitePlus
S1249 Phosphorylation PhosphoSitePlus
S1253 Phosphorylation PhosphoSitePlus
S1255 Phosphorylation PhosphoSitePlus
Y1300 Phosphorylation PhosphoSitePlus
S1303 Phosphorylation PhosphoSitePlus
Y1312 Phosphorylation PhosphoSitePlus
R1393 Methylation PhosphoSitePlus
S1402 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1414 Phosphorylation PhosphoSitePlus
K1458 Methylation PhosphoSitePlus
R1513 Methylation PhosphoSitePlus
R1527 Methylation PhosphoSitePlus
R1534 Methylation PhosphoSitePlus
R1541 Methylation PhosphoSitePlus
K1596 Sumoylation PhosphoSitePlus
T1650 Phosphorylation PhosphoSitePlus
K1652 Ubiquitination PhosphoSitePlus
Y1658 Phosphorylation PhosphoSitePlus
R1690 Methylation PhosphoSitePlus
Y1695 Phosphorylation PhosphoSitePlus
R1698 Methylation PhosphoSitePlus
Y1728 Phosphorylation PhosphoSitePlus
R1757 Methylation PhosphoSitePlus
R1758 Methylation PhosphoSitePlus
S1770 Phosphorylation PhosphoSitePlus
Y1775 Phosphorylation PhosphoSitePlus
R1792 Methylation PhosphoSitePlus
K1813 Acetylation PhosphoSitePlus
K1824 Acetylation PhosphoSitePlus
K1857 Ubiquitination PhosphoSitePlus
S1870 Phosphorylation PhosphoSitePlus
Y1874 Phosphorylation PhosphoSitePlus
T1877 Phosphorylation PhosphoSitePlus
K1890 Acetylation PhosphoSitePlus
K1891 Acetylation PhosphoSitePlus
K1893 Acetylation PhosphoSitePlus
K1894 Acetylation PhosphoSitePlus
K1895 Acetylation PhosphoSitePlus
T1966 Phosphorylation PhosphoSitePlus
S2035 Phosphorylation PhosphoSitePlus
Y2039 Phosphorylation PhosphoSitePlus
Y2080 Phosphorylation PhosphoSitePlus
Y2087 Phosphorylation PhosphoSitePlus
T2123 Phosphorylation PhosphoSitePlus
K2138 Acetylation PhosphoSitePlus
K2138 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S371 Phosphorylation HPRD 20068231
S660 Phosphorylation HPRD 20058876
S756 Phosphorylation HPRD 19664995
S827 Phosphorylation HPRD 20058876
S829 Phosphorylation HPRD 18669648, 19664995, 20068231
S1119 Phosphorylation HPRD 17081983, 20068231
Y1695 Phosphorylation HPRD 20068231
Y1728 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S192 L192 Biomuta [ cosmic ]
S194 Y194 Biomuta DOID:1324 / lung cancer [ cosmic ]
S236 P236 Biomuta DOID:1612 / breast cancer [ cosmic ]
K317 E317 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K318 T318 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K318 Q318 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K318 R318 Biomuta DOID:1612 / breast cancer [ cosmic ]
S660 L660 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
S660 A660 Biomuta DOID:3571 / liver cancer [ cosmic ]
S752 T752 Biomuta DOID:1324 / lung cancer [ cosmic ]
R789 C789 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R814 Q814 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R814 L814 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S827 C827 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R831 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K841 R841 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S860 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S871 N871 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K875 N875 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S905 C905 Biomuta DOID:1540 / parathyroid carcinoma [ cosmic ]
R1041 H1041 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1148 * Biomuta DOID:363 / uterine cancer [ cosmic ]
R1698 H1698 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R1698 C1698 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1758 I1758 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1792 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1792 Q1792 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K1824 I1824 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1857 N1857 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S1870 I1870 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y2080 C2080 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]