iPTMnet Report P49746 THBS3

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P49746 / TSP3_HUMAN
Protein Name	Thrombospondin-3 precursor
Gene Name	Name: THBS3 Synonyms:TSP3;
Organism	Homo sapiens (Human)

PRO ID	PR:P49746 DAG View
PRO Name	thrombospondin-3 (human)
Definition	A thrombospondin-3 that is encoded in the genome of human.
Short Label	hTHBS3
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P49746 (THBS3) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S186	Phosphorylation		score1	PhosphoSitePlus
	S194	Phosphorylation		score1	PhosphoSitePlus
	T228	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	17287340
	Y348	Phosphorylation		score1	PhosphoSitePlus
	T351	Phosphorylation		score1	PhosphoSitePlus
	N407	N-Glycosylation		score1	GlyGen	23090970, 29741879, 24190977
	T623	Phosphorylation		score1	PhosphoSitePlus
	N937	N-Glycosylation		score1	GlyGen	23090970, 29741879, 24190977

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T228	Phosphorylation		score0	HPRD	17287340
	N407	N-Glycosylation		score1	PRO	29741879

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S186	Y186	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
S194	P194	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
T351	I351	Biomuta		DOID:4606 / bile duct cancer [ cosmic ]