iPTMnet Report for P49642 (PRIM1)
Protein Information
UniProt AC / UniProt ID | P49642 / PRI1_HUMAN |
Protein Name | DNA primase small subunit |
Gene Name | Name: PRIM1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P49642 |
PRO Name | DNA primase small subunit (human) |
Definition | A DNA primase small subunit that is encoded in the genome of human. |
Short Label | hPRIM1 |
Category | organism-gene |
P49642 (PRIM1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22223895 | ||
T3 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y16 | Phosphorylation | score0 | HPRD | 20068231 | ||
K68 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
K77 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
S124 | Phosphorylation | score1 | PhosphoSitePlus | |||
K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
K147 | Ubiquitination | score1 | PhosphoSitePlus | |||
K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y188 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
K214 | Ubiquitination | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
K242 | Ubiquitination | score1 | PhosphoSitePlus | |||
K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
K284 | Ubiquitination | score1 | PhosphoSitePlus | |||
S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
S319 | Phosphorylation | score1 | PhosphoSitePlus | |||
K326 | Ubiquitination | score1 | PhosphoSitePlus | |||
S331 | Phosphorylation | score1 | PhosphoSitePlus | |||
S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
T362 | Phosphorylation | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
K377 | Ubiquitination | score1 | PhosphoSitePlus | |||
K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
T386 | Phosphorylation | score1 | PhosphoSitePlus | |||
S387 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y391 | Phosphorylation | score1 | PhosphoSitePlus | |||
K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K221 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S387 | N387 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |