iPTMnet Report for P48651 (PTDSS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P48651 / PTSS1_HUMAN
Protein Name Phosphatidylserine synthase 1
Gene Name Name: PTDSS1
Synonyms:KIAA0024,PSSA;
Organism Homo sapiens (Human)

PRO ID PR:P48651
DAG View
PRO Name phosphatidylserine synthase 1 (human)
Definition A phosphatidylserine synthase 1 that is encoded in the genome of human.
Short Label hPTDSS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P48651 (PTDSS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 25944712
S3 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
C153 Methylation IEDB 31844290
C213 Methylation IEDB 31844290
K251 Ubiquitination PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
T379 Phosphorylation IEDB 32387766
T415 Phosphorylation PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
S417 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
T423 Phosphorylation PhosphoSitePlus
Y424 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S425 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...18220336
S429 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus   UniProt 18691976, 20068231, 19369195
S454 Phosphorylation PhosphoSitePlus   UniProt 20068231
S455 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S462 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 19691289
T415 Phosphorylation HPRD 17081983
Y416 Phosphorylation HPRD 17081983
S417 Phosphorylation HPRD 18669648
T423 Phosphorylation HPRD 18691976, 17081983
S425 Phosphorylation HPRD 18669648, 19007248
S442 Phosphorylation HPRD 19651622, 18691976, 20068231
S454 Phosphorylation HPRD 17081983, 20068231
S455 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 Y3 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K12 N12 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y17 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
K261 E261 Biomuta DOID:9256 / colorectal cancer [ cosmic ]