iPTMnet Report for P48551 (IFNAR2)
Protein Information
| UniProt AC / UniProt ID | P48551 / INAR2_HUMAN |
| Protein Name | Interferon alpha/beta receptor 2 precursor |
| Gene Name | Name: IFNAR2 Synonyms:IFNABR,IFNARB; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P48551 |
| PRO Name | interferon alpha/beta receptor 2 (human) |
| Definition | An interferon alpha/beta receptor 2 that is encoded in the genome of human. |
| Short Label | hIFNAR2 |
| Category | organism-gene |
DAG ViewP48551 (IFNAR2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N87 | N-Glycosylation | score3 | GlyGen UniProt | 8181059 | ||
| C93 | Methylation | score1 | IEDB | 31844290 | ||
| N188 | N-Glycosylation | score1 | GlyGen | 29671580 | ||
| N192 | N-Glycosylation | score4 | GlyGen UniProt | 8181059, 24190977 | ||
| T204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N205 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T249 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y269 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y316 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T326 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y337 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 11682488, 12105218 | ||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S384 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K399 | Acetylation | score1 | PhosphoSitePlus | |||
| S400 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 15659558 | ||
| Y411 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15659558 | ||
| S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y512 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 11682488, 12105218 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N188 | N-Glycosylation | score1 | PRO | 29671580 | ||
| K399 | Acetylation | PR:Q92793 (hCREBBP) | score2 | PRO | 17923090 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K323 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000028646 (hIFNAR2/iso:1/Ac:1) | acK399 | PR:Q92793 (hCREBBP) | PRO | 17923090 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N87 | K87 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T204 | R204 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y269 | H269 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| Y269 | C269 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| Y306 | S306 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| Y318 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S324 | I324 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
