iPTMnet Report for P47870 (GABRB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P47870 / GBRB2_HUMAN
Protein Name Gamma-aminobutyric acid receptor subunit beta-2 precursor
Gene Name Name: GABRB2
Organism Homo sapiens (Human)

PRO ID PR:P47870
DAG View
PRO Name gamma-aminobutyric acid receptor subunit beta-2 (human)
Definition A gamma-aminobutyric acid receptor subunit beta-2 that is encoded in the genome of human.
Short Label hGABRB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P47870 (GABRB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Ubiquitination PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
Y362 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
Y372 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
Y441 Phosphorylation PhosphoSitePlus
S472 Phosphorylation P31749 (AKT1) neXtProt 12818177
Site PTM Type PTM Enzyme Score Source PMID
Y98 Phosphorylation PhosphoSitePlus
S434 Phosphorylation HPRD 1334482
Site PTM Type PTM Enzyme Score Source PMID
S472 Phosphorylation HPRD 1334482


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y98 N98 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y98 C98 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K126 E126 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K126 N126 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K136 N136 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S347 I347 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T389 A389 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y441 * Biomuta DOID:4159 / skin cancer [ cosmic ]