iPTMnet Report for P47755 (CAPZA2)
Protein Information
UniProt AC / UniProt ID | P47755 / CAZA2_HUMAN |
Protein Name | F-actin-capping protein subunit alpha-2 |
Gene Name | Name: CAPZA2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P47755 |
PRO Name | F-actin-capping protein subunit alpha-2 (human) |
Definition | An F-actin-capping protein subunit alpha-2 that is encoded in the genome of human. |
Short Label | hCAPZA2 |
Category | organism-gene |
P47755 (CAPZA2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
S9 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
K19 | Acetylation | score1 | PhosphoSitePlus | |||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
T63 | Phosphorylation | score1 | PhosphoSitePlus | |||
T77 | Phosphorylation | score1 | IEDB | 32387766 | ||
K86 | Acetylation | score1 | PhosphoSitePlus | |||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Acetylation | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
C111 | Methylation | score1 | IEDB | 31844290 | ||
K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
T142 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y144 | Phosphorylation | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
C157 | Methylation | score1 | IEDB | 31844290 | ||
T180 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y198 | Phosphorylation | score1 | PhosphoSitePlus | |||
K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
K256 | Methylation | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
K268 | Sumoylation | score1 | PhosphoSitePlus | |||
K268 | Ubiquitination | score1 | PhosphoSitePlus | |||
K273 | Acetylation | score1 | PhosphoSitePlus | |||
K273 | Sumoylation | score1 | PhosphoSitePlus | |||
K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y277 | Phosphorylation | score1 | PhosphoSitePlus | |||
K278 | Acetylation | score1 | PhosphoSitePlus | |||
K278 | Sumoylation | score1 | PhosphoSitePlus | |||
K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
K281 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K86 | M86 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K91 | N91 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
C111 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y144 | C144 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
Y144 | H144 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] | |
Y198 | F198 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
Y277 | C277 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |