iPTMnet Report for P47755 (CAPZA2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P47755 / CAZA2_HUMAN
Protein Name F-actin-capping protein subunit alpha-2
Gene Name Name: CAPZA2
Organism Homo sapiens (Human)

PRO ID PR:P47755
DAG View
PRO Name F-actin-capping protein subunit alpha-2 (human)
Definition An F-actin-capping protein subunit alpha-2 that is encoded in the genome of human.
Short Label hCAPZA2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P47755 (CAPZA2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S9 Phosphorylation PhosphoSitePlus   UniProt 23186163
K13 Ubiquitination PhosphoSitePlus
K19 Acetylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
T77 Phosphorylation IEDB 32387766
K86 Acetylation PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K97 Acetylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
C111 Methylation IEDB 31844290
K133 Ubiquitination PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
Y144 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
C157 Methylation IEDB 31844290
T180 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K256 Methylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K268 Sumoylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
K273 Sumoylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K278 Acetylation PhosphoSitePlus
K278 Sumoylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 19413330, 19651622, 20058876, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K86 M86 Biomuta DOID:3571 / liver cancer [ cosmic ]
K91 N91 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
C111 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y144 C144 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y144 H144 Biomuta DOID:5158 / pleural cancer [ cosmic ]
Y198 F198 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y277 C277 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]